Clinical Immunology
Strong EvidenceChronic low-grade inflammation, cytokine storms, and resolution pathways.
Vagus nerve stimulation benefits explained by a physician. Invasive vs non-invasive VNS, cold exposure, HRV measurement, and clinical evidence for inflammation and depression.
Semax is a synthetic ACTH-derived peptide that upregulates BDNF, enhances focus and memory, and offers neuroprotection — used clinically in Russia for decades.
Physician's guide to PEMF frequency selection—from 1 Hz sleep protocols to 100 Hz inflammation reduction. Know which settings match your condition.
Dr. Douwes reviews hyperbaric oxygen therapy (HBOT): how it works, what the clinical evidence says for longevity, post-COVID, Lyme, and neurological recovery.
Low-dose naltrexone modulates immune function and reduces neuroinflammation. Evidence-based overview of LDN dosing, mechanisms, and clinical applications.
A physician's evidence-based breakdown of cold plunge physiology — from norepinephrine spikes to metabolic shifts, and how to dose cold water immersion safely.
Dr. Douwes reviews transcranial photobiomodulation for depression — mechanisms, clinical trial data, dosing protocols, and how it fits an integrative mental health strategy.
How pulsed electromagnetic field therapy supports pain relief and inflammation reduction in Lyme disease — mechanism, clinical evidence, and practical considerations.
How the KPV tripeptide reduces gut inflammation. NF-kB inhibition, PepT1 uptake, IBD and colitis evidence, oral dosing, and clinical observations.
What causes brain fog in Lyme disease — Johns Hopkins PET scan findings showing glial activation, neuroinflammation mechanisms, and treatment implications.
Evidence-based omega-3 dosing for inflammation. How much EPA and DHA for joint pain, cardiovascular inflammation, neuroinflammation, and autoimmune conditions. Physician protocols.
A physician's evidence-based protocol for reducing chronic inflammation through diet, lifestyle, and targeted supplementation.
How the vagus nerve controls inflammation through the cholinergic anti-inflammatory pathway. Mechanism, clinical significance, and implications for chronic illness.
How chronic low-grade inflammation drives disease, what causes it, and evidence-based strategies to address it. By Dr. Julian Douwes.
Why histamine intolerance is a systemic condition, not just allergies. Mechanisms, diagnostic pitfalls, gut-immune connections, and treatment strategies from clinical experience.
A physician's guide to MCAS — mechanism, symptoms, diagnostic criteria, treatment, and the connection to Lyme, mold, and EBV. Based on clinical experience treating patients with complex multi-system illness.
The bioavailability problem with curcumin explained. Comparing Meriva, Longvida, BCM-95, Theracurmin, liposomal, and piperine forms. Dosing by condition.
What causes a cytokine storm, how it damages the body, and what physicians can do about it. A clinical explanation by Dr. Julian Douwes.
The bidirectional gut-brain axis governs mood, cognition, and immune balance. Dr. Julian Douwes explains the science and integrative protocols for restoring this critical communication pathway.
