Evidence Explorer · Library

Peptide library, A–Z

Every peptide and related compound reviewed on this site, with the evidence level stated in its article's At a Glance table. Most of these compounds have little or no controlled human data, and the list says so.

80 compounds10 strong12 moderate9 emerging49 limited

Peptide Evidence Checker: one compound’s evidence, FDA, EU and WADA status and top safety flag on a single card, or two side by side.

What the evidence levels mean
Strong evidence
Large randomised trials or an approval for a defined use.
Moderate evidence
Several controlled human studies, or solid human pharmacology without outcome trials.
Emerging evidence
Early human trials or mixed results; the picture may change.
Limited evidence
Animal, cell or anecdotal data; little or no controlled human evidence.

A level describes the best evidence for the compound's main use. Where an article limits it ("for EPP", "for GH pharmacology"), the scope is shown next to the label. Levels are a summary, not a recommendation.

80 compounds

0–9

  • 5-Amino-1MQ

    NNMT inhibitor

    5-Amino-1MQ blocks NNMT, raising NAD+ and suppressing fat storage in mice.

    Limited evidence Weight & metabolism

A

  • Abaloparatide

    Tymlos

    Abaloparatide is an approved PTHrP analogue that builds bone and cut new vertebral fractures by 86% in the ACTIVE trial.

    Strong evidence Hormones, bone & sexual health

  • ACE-031

    ramatercept

    ACE-031 added 3.3% lean mass from one dose, then its Duchenne trial was halted over nosebleeds and telangiectasias.

    Emerging evidence Growth hormone & muscle

  • Adamax

    Adamax is a designer Semax analog with an adamantane cap borrowed from P021.

    Limited evidence Brain & mood

  • Adipotide

    FTPP

    Adipotide kills the blood supply of white fat.

    Limited evidence Weight & metabolism

  • AHK-Cu

    AHK-Cu is a copper tripeptide marketed for hair growth.

    Limited evidence Skin & hair

  • AICAR

    acadesine

    AICAR activates AMPK and improved endurance in untrained mice.

    Moderate evidence for human safety and pharmacodynamics Weight & metabolism

  • AOD-9604

    AOD 9604 is a modified fragment of human growth hormone that targets fat metabolism without raising IGF-1.

    Limited evidence Weight & metabolism

  • ARA-290

    cibinetide

    ARA-290 (cibinetide) is an EPO-derived peptide tested in small trials for sarcoidosis and diabetic small fiber neuropathy.

    Emerging evidence Healing & repair

B

  • Bimagrumab

    with semaglutide

    Activin type II receptor antibody tested with semaglutide to protect lean mass during weight loss.

    Emerging evidence Weight & metabolism

  • BPC-157

    Synthetic 15-amino-acid peptide from a gastric protein, studied for tissue repair mainly in animals.

    Limited evidence Healing & repair

  • Bronchogen

    Bronchogen is the Khavinson tetrapeptide Ala-Glu-Asp-Leu marketed for the bronchi.

    Limited evidence Bioregulators

C

  • Cardiogen

    Cardiogen (Ala-Glu-Asp-Arg) is a Khavinson tetrapeptide sold for the heart.

    Limited evidence Bioregulators

  • Cartalax

    Cartalax (Ala-Glu-Asp) is a Khavinson Cytogen marketed for cartilage and joints.

    Limited evidence Bioregulators

  • Cerebrolysin

    Cerebrolysin is a pig-brain peptide drug licensed in Austria and other countries.

    Moderate evidence Brain & mood

  • CJC-1295 / Ipamorelin

    A GHRH analogue and a ghrelin-receptor agonist, combined to raise pulsatile growth hormone release.

    Limited evidence Growth hormone & muscle

  • Collagen peptides

    Hydrolysed collagen supplements for joints, skin and gut: types, trial data and dosing.

    Moderate evidence Skin & hair

  • Cortagen

    Cortagen (Ala-Glu-Asp-Pro) is a Khavinson brain-cortex tetrapeptide.

    Limited evidence Bioregulators

  • Crystagen

    Crystagen (Glu-Asp-Pro) is a Khavinson Cytogen sold for the immune system.

    Limited evidence Bioregulators

D

  • Dihexa

    Synthetic hexapeptide acting on HGF/c-Met signalling, studied only in animals.

    Limited evidence Brain & mood

  • DSIP

    delta sleep-inducing peptide

    Delta sleep-inducing peptide, an endogenous neuropeptide tested for sleep in small trials decades ago.

    Limited evidence Brain & mood

E

  • Eloralintide

    Eloralintide (LY3841136) is a selective amylin receptor agonist.

    Emerging evidence Weight & metabolism

  • Epithalon

    epitalon

    Synthetic tetrapeptide from the Khavinson programme, studied for telomerase and aging mainly in cells and animals.

    Limited evidence Longevity & mitochondria

F

  • Follistatin

    FST-344

    Follistatin blocks myostatin and activin.

    Emerging evidence for AAV follistatin gene therapy in specific muscle diseases Growth hormone & muscle

  • FOXO4-DRI

    FOXO4-DRI cleared senescent cells in aged mice in 2017.

    Limited evidence Longevity & mitochondria

G

  • GHK-Cu

    copper peptide

    Copper-binding tripeptide used in topical skincare; injectable use is untested in trials.

    Limited evidence Skin & hair

  • GHRP-2

    pralmorelin

    GHRP-2 is a ghrelin-receptor agonist that raises growth hormone strongly and is a licensed diagnostic agent in Japan.

    Moderate evidence for what it does to hormones Growth hormone & muscle

  • GHRP-6

    GHRP-6 is the first well-characterised ghrelin-receptor agonist.

    Moderate evidence for GH pharmacology and pharmacokinetics in humans Growth hormone & muscle

  • GLOW blend

    GLOW is a vendor blend, usually GHK-Cu 50 mg, BPC-157 10 mg and TB-500 10 mg.

    Limited evidence Blends

  • GLP-1 (7-36) amide

    native GLP-1, pure GLP-1

    Native GLP-1 7-36 amide is the real human incretin hormone — and it lasts about two minutes in blood.

    Moderate evidence for the physiology Weight & metabolism

  • Glutathione

    The body's main intracellular antioxidant tripeptide; IV, liposomal, nebulised and intranasal routes compared.

    Moderate evidence Longevity & mitochondria

  • Gonadorelin

    Gonadorelin is native GnRH with a 2 to 20 minute half-life.

    Strong evidence for diagnostic testing and for pulsatile pump therapy in GnRH deficiency Hormones, bone & sexual health

H

  • Hexarelin

    Hexarelin releases more growth hormone than any common GHRP, binds CD36 in the heart, and blunts its own response within weeks.

    Moderate evidence for human GH pharmacology Growth hormone & muscle

  • HGH Fragment 176-191

    HGH Fragment 176-191 is sold as a fat-loss peptide and is not the same molecule as AOD-9604.

    Limited evidence Weight & metabolism

  • Humanin

    Peptide encoded in mitochondrial DNA; protective in cell and animal studies, no human treatment trials.

    Limited evidence Longevity & mitochondria

I

  • IGF-1 LR3

    IGF-1 LR3 is an engineered IGF-1 analogue that evades binding proteins.

    Limited evidence Growth hormone & muscle

  • Ipamorelin

    Ipamorelin selectively amplifies GH pulses without raising cortisol or prolactin.

    Limited evidence Growth hormone & muscle

K

  • Khavinson bioregulators (overview)

    Thymalin, Cytomax, Cytogen

    Khavinson's organ extracts and short synthetic peptides, and the cyclic protocol built around them.

    Limited evidence Bioregulators

  • Kisspeptin

    Neuropeptide upstream of GnRH, LH and FSH, studied in fertility and testosterone protocols.

    Emerging evidence Hormones, bone & sexual health

  • KLOW blend

    KLOW is a vendor blend of GHK-Cu 50 mg, BPC-157, TB-500 and KPV 10 mg each.

    Limited evidence Blends

  • KPV

    Anti-inflammatory tripeptide fragment of alpha-MSH, studied for gut inflammation in animals.

    Limited evidence Immune & inflammation

L

  • Liraglutide

    Saxenda, Victoza

    Liraglutide (Saxenda, Victoza) was the first GLP-1 approved for obesity.

    Strong evidence Weight & metabolism

  • Livagen

    Livagen (Lys-Glu-Asp-Ala) is a Khavinson liver tetrapeptide.

    Limited evidence Bioregulators

  • LL-37

    cathelicidin

    The only human cathelicidin, an antimicrobial peptide studied for infections and biofilms.

    Limited evidence Immune & inflammation

M

  • Mazdutide

    Mazdutide (Xinermei, IBI362) is a GLP-1/glucagon dual agonist approved in China.

    Strong evidence within the Chinese population Weight & metabolism

  • Melanotan 1

    afamelanotide, Scenesse

    Melanotan 1 is afamelanotide, approved as the 16 mg Scenesse implant for EPP.

    Moderate evidence for EPP Skin & hair

  • Melanotan 2

    MT-II

    Melanotan 2 (MT-II) tans skin and triggers erections via melanocortin receptors.

    Limited evidence Skin & hair

  • MGF

    mechano growth factor

    MGF is the IGF-1Ec splice variant switched on by mechanical loading.

    Limited evidence Growth hormone & muscle

  • MK-677

    ibutamoren

    Oral ghrelin mimetic that raises growth hormone and IGF-1; never approved as a medicine.

    Moderate evidence for raising GH Growth hormone & muscle

  • MOTS-c

    MOTS-c is a mitochondria-encoded peptide that activates AMPK, improves insulin sensitivity, and may extend healthspan.

    Limited evidence Longevity & mitochondria

N

  • NAD+

    IV and injections

    Coenzyme for energy metabolism and DNA repair, given by IV infusion or injection.

    Moderate evidence Longevity & mitochondria

O

  • Ovagen

    Ovagen (Glu-Asp-Leu) is a Khavinson Cytogen sold for liver and gut.

    Limited evidence Bioregulators

  • Oxytocin

    Intranasal oxytocin has hundreds of trials and a replication problem.

    Moderate evidence for pharmacology and tolerability Brain & mood

P

  • P021

    P021 is a CNTF-derived peptide that boosted neurogenesis and memory in mice and rats.

    Limited evidence Brain & mood

  • PE-22-28

    mini-spadin

    PE-22-28 is a 7-amino-acid spadin analog that blocks the TREK-1 channel and acted as a fast antidepressant in mice.

    Limited evidence Brain & mood

  • PEG-MGF

    PEG-MGF is PEGylated mechano growth factor, built to fix MGF's short half-life.

    Limited evidence Growth hormone & muscle

  • Pentosan polysulfate

    Elmiron

    Semi-synthetic polysaccharide approved for interstitial cystitis, studied in knee osteoarthritis, with a retinal risk.

    Strong evidence Healing & repair

  • Pinealon

    Pinealon (Glu-Asp-Arg) is a Khavinson tripeptide sold for the brain.

    Limited evidence Bioregulators

  • PNC-27

    PNC-27 is a p53-derived peptide studied in cell lines and mice.

    Limited evidence Cancer research

  • Prostamax

    Prostamax (Lys-Glu-Asp-Pro) is a Khavinson tetrapeptide sold for the prostate.

    Limited evidence Bioregulators

  • PT-141

    bremelanotide, Vyleesi

    Melanocortin agonist (bremelanotide) approved by the FDA for low sexual desire in premenopausal women.

    Strong evidence for HSDD in premenopausal women Hormones, bone & sexual health

R

  • Retatrutide

    Investigational weekly GIP/GLP-1/glucagon triple agonist: phase 2 weight-loss data, titration and side effects.

    Strong evidence for weight loss Weight & metabolism

S

  • Selank

    Tuftsin-derived heptapeptide licensed in Russia as an anxiolytic.

    Limited evidence Brain & mood

  • Semaglutide

    Ozempic, Wegovy, Rybelsus

    Once-weekly GLP-1 receptor agonist approved for type 2 diabetes and obesity, with cardiovascular outcome data.

    Strong evidence Weight & metabolism

  • Semax

    ACTH-derived heptapeptide used in Russia for stroke and cognition; raises BDNF in animal studies.

    Limited evidence Brain & mood

  • Sermorelin

    Geref

    GHRH analogue that stimulates the pituitary to release growth hormone; once approved as Geref, withdrawn in 2008.

    Limited evidence Growth hormone & muscle

  • SNAP-8

    acetyl octapeptide-3

    SNAP-8 (acetyl octapeptide-3) is a cosmetic anti-wrinkle peptide modelled on SNAP-25.

    Limited evidence Skin & hair

  • SS-31

    elamipretide

    SS-31 is a tetrapeptide that targets cardiolipin in the inner mitochondrial membrane.

    Emerging evidence Longevity & mitochondria

T

  • TB-500

    thymosin beta-4 fragment

    Synthetic fragment of thymosin beta-4 sold for tissue repair; no published human trials.

    Limited evidence Healing & repair

  • Tesamorelin

    Egrifta

    Tesamorelin is the only GHRH analogue with phase 3 trials and an FDA approval.

    Strong evidence for visceral fat reduction in HIV-associated lipodystrophy Growth hormone & muscle

  • Testagen

    Testagen (Lys-Glu-Asp-Gly) is sold as a testicular bioregulator, but its PubMed studies describe a pituitary-derived peptide tested in chickens.

    Limited evidence Bioregulators

  • Thymogen

    Thymogen (Glu-Trp, oglufanide) is a licensed immunostimulant in Russia.

    Limited evidence Bioregulators

  • Thymosin Alpha-1

    thymalfasin, Zadaxin

    Thymic peptide (thymalfasin) licensed as an immune modulator in some countries outside the US and EU.

    Emerging evidence Immune & inflammation

  • Thymulin

    Thymulin is a zinc-dependent thymic nonapeptide that falls with age.

    Limited evidence Immune & inflammation

  • Tirzepatide

    Mounjaro, Zepbound

    Once-weekly dual GIP/GLP-1 receptor agonist approved for type 2 diabetes (Mounjaro) and obesity (Zepbound).

    Strong evidence Weight & metabolism

  • Tri-Heal Max

    Tri-Heal Max is a 45 mg vendor blend of TB-500 25 mg, BPC-157 10 mg and KPV 10 mg.

    Limited evidence Blends

V

  • Vesugen

    Vesugen (Lys-Glu-Asp) is a Khavinson Cytogen sold for blood vessels.

    Limited evidence Bioregulators

  • Vilon

    Vilon (Lys-Glu) is a Khavinson thymus dipeptide.

    Limited evidence Bioregulators

  • VIP

    vasoactive intestinal peptide

    Vasoactive intestinal peptide (VIP) is a neuropeptide used in the final phase of CIRS treatment.

    Limited evidence Immune & inflammation

  • VK2735

    VK2735 is a dual GIP/GLP-1 agonist from Viking Therapeutics, in Phase 3 as a weekly injection and tested in Phase 2 as a daily tablet.

    Emerging evidence Weight & metabolism

Information only, not medical advice. Evidence levels summarise the published research; they do not mean a compound is safe, legal or appropriate for you. Back to Peptide Therapy