Infectiology

Emerging Evidence

Post-COVID / Long COVID

Microclots, spike protein persistence, brain fog, and treatment approaches.

22 articles · 179 min total
01

Therapeutic Apheresis: New Indications and Emerging Evidence in 2026

A clinical review of therapeutic apheresis beyond established autoimmune uses—covering neurological, metabolic, and post-infectious indications supported by 2025-2026 evidence.

Therapeutic Apheresis: New Indications and Emerging Evidence in 2026
02

Low-Dose Naltrexone for Long COVID and Post-Viral Fatigue: Clinical Evidence and Protocol

LDN reduces neuroinflammation and immune dysregulation driving long COVID fatigue. Clinical evidence, dosing protocol, and how LDN fits a multimodal recovery plan.

Low-Dose Naltrexone for Long COVID and Post-Viral Fatigue: Clinical Evidence and Protocol
03

5-HTP and Tryptophan: A Physician's Guide to Serotonin Precursors for Sleep, Mood, and Brain Fog

Dr. Julian Douwes explains 5-HTP vs tryptophan for serotonin support — dosing, safety, interactions, and clinical use in Lyme disease and post-COVID patients.

5-HTP and Tryptophan: A Physician's Guide to Serotonin Precursors for Sleep, Mood, and Brain Fog
04

Benfotiamine for Peripheral Neuropathy: A Physician's Evidence Review

Fat-soluble thiamine that crosses cell membranes conventional B1 cannot. How benfotiamine repairs peripheral nerves, reduces oxidative stress, and supports recovery in Lyme, diabetes, and post-COVID neuropathy.

Benfotiamine for Peripheral Neuropathy: A Physician's Evidence Review
05

Lumbrokinase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?

Comparing lumbrokinase and nattokinase for fibrin clearance, biofilm disruption, post-COVID microclots, and cardiovascular health — with clinical dosing guidance.

Lumbrokinase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?
06

Hyperbaric Oxygen Therapy for Long COVID: Evidence, Protocol, and What to Expect

A physician's guide to HBOT for Long COVID — covering the mechanisms, clinical trial data, patient selection, session protocols, and realistic outcome expectations.

Hyperbaric Oxygen Therapy for Long COVID: Evidence, Protocol, and What to Expect
07

Mitochondrial Dysfunction: Root Causes, Testing, and Evidence-Based Treatment

How mitochondrial dysfunction drives fatigue, brain fog, and chronic illness — plus clinical testing and protocols to restore cellular energy production.

Mitochondrial Dysfunction: Root Causes, Testing, and Evidence-Based Treatment
08

Lumbrokinase: The Fibrinolytic Enzyme Your Doctor Probably Hasn't Mentioned

Lumbrokinase is a potent fibrinolytic enzyme with emerging evidence for post-COVID microclots, Lyme biofilms, and chronic inflammation. A physician's clinical overview.

Lumbrokinase: The Fibrinolytic Enzyme Your Doctor Probably Hasn't Mentioned
09

L-Glutamine for Gut Health: Leaky Gut, Mucosal Repair, and Clinical Dosing

L-glutamine is the intestinal lining's primary fuel source. Explore the clinical evidence for leaky gut, Lyme dysbiosis, post-COVID recovery, and optimal dosing protocols.

L-Glutamine for Gut Health: Leaky Gut, Mucosal Repair, and Clinical Dosing
10

POTS and Dysautonomia: A Functional Medicine Protocol

POTS and dysautonomia affect millions after infection or long COVID. This functional medicine protocol addresses root causes beyond symptom management.

POTS and Dysautonomia: A Functional Medicine Protocol
11

Hyperbaric Oxygen Therapy for Longevity and Recovery: A Physician's Review

Dr. Douwes reviews hyperbaric oxygen therapy (HBOT): how it works, what the clinical evidence says for longevity, post-COVID, Lyme, and neurological recovery.

Hyperbaric Oxygen Therapy for Longevity and Recovery: A Physician's Review
12

Ozone Therapy Evidence: What the Clinical Research Actually Shows

A physician's analysis of ozone therapy evidence across chronic infections, post-COVID, wound healing, and autoimmunity — mechanisms, delivery methods, and realistic expectations.

Ozone Therapy Evidence: What the Clinical Research Actually Shows
13

H.E.L.P. Apheresis vs INUSpheresis: Which Blood Filtration Therapy?

A physician's comparison of H.E.L.P. Apheresis and INUSpheresis — filtering mechanisms, indications, evidence, cost, and which patients benefit from each approach.

H.E.L.P. Apheresis vs INUSpheresis: Which Blood Filtration Therapy?
14

Brain Fog Treatment: A Physician's Complete Guide

Brain fog treatment options from neuroinflammation workup to neuromodulation. Causes include post-COVID, Lyme, MCAS, and mold. TPS, NAD+, and hyperbaric oxygen covered.

Brain Fog Treatment: A Physician's Complete Guide
15

H.E.L.P. Apheresis: How Blood Filtration Removes What Shouldn't Be There

How H.E.L.P. apheresis filters LDL, fibrinogen, CRP, and microclots from your blood. Mechanism, session details, evidence, and clinical experience at Klinik St. Georg.

H.E.L.P. Apheresis: How Blood Filtration Removes What Shouldn't Be There
16

Nattokinase: The Fibrinolytic Enzyme for Microclots

Evidence-based guide to nattokinase for fibrinolysis and microclots. Mechanism, dosing, post-COVID relevance, combination with serrapeptase, and safety with blood thinners.

Nattokinase: The Fibrinolytic Enzyme for Microclots
17

Microclots and Endothelial Dysfunction

How microclots and damaged blood vessel linings drive post-COVID symptoms. Dr. Beate Jaeger's research and clinical implications.

Microclots and Endothelial Dysfunction
18

Post-COVID Syndrome: Our Treatment Approach

How we treat Long COVID and post-COVID syndrome. Mechanisms, diagnostics, and a multimodal treatment program grounded in clinical experience.

Post-COVID Syndrome: Our Treatment Approach
19

Post-COVID Brain Fog: Mechanisms and Treatment

Why COVID-19 causes persistent cognitive dysfunction and what can be done about it. Mechanisms, assessment, and treatment strategies.

Post-COVID Brain Fog: Mechanisms and Treatment
20

Apheresis for Long COVID: Removing Microclots and Restoring Circulation

How H.E.L.P. apheresis removes microclots and inflammatory mediators in Long COVID patients. Session protocols, evidence from Pretorius research, and clinical experience at Klinik St. Georg.

Apheresis for Long COVID: Removing Microclots and Restoring Circulation
21

Long COVID: Symptoms, Mechanisms, and What Actually Helps

A clinical guide to Long COVID symptoms and treatment based on 500+ patients. Microclots, spike protein persistence, endothelial dysfunction, and the therapies that produce measurable results.

Long COVID: Symptoms, Mechanisms, and What Actually Helps
22

Post-COVID Recovery Protocol

An evidence-based recovery protocol addressing inflammation, clotting, energy, and immune regulation after COVID-19. By Dr. Julian Douwes.

Post-COVID Recovery Protocol
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