BPC-157 Contraindications: Who Should Not Use This Peptide
A clinical guide to BPC-157 contraindications, relative cautions, and drug interactions — covering cancer patients, transplant recipients, pregnancy, and autoimmune conditions.
Clinical Immunology
Moderate EvidenceGut-Immune Axis
The microbiome-immune connection and mucosal immunity.
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Psoriasis: An Integrative Medicine Protocol
A functional medicine approach to psoriasis addressing gut-skin axis, immune modulation, LDN, photobiomodulation, and dietary strategies—backed by clinical evidence.
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Low Dose Naltrexone for Crohn's Disease and Ulcerative Colitis
How LDN modulates gut immunity, reduces inflammation, and offers a low-risk adjunct in IBD — dosing, evidence hierarchy, patient selection, and monitoring.
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Probiotics for Allergic Disease: From Adjunct Supplement to Immune-Modifying Strategy
How specific probiotic strains shift Th2-dominant immune responses in allergic rhinitis, eczema, food allergy, and asthma — a clinical guide to strain selection and protocol design.
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Lactoferrin: Clinical Evidence, Dosing, and Immune Benefits
A physician's guide to lactoferrin—how this iron-binding glycoprotein modulates immunity, supports gut barrier integrity, and may benefit chronic illness patients.
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Urolithin A Dosage: Physician's Guide to Timing, Protocol, and the Clinical Evidence
Physician-reviewed urolithin A dosage guide: optimal dose from 500mg to 2g, timing, cycling, and stacking protocols backed by clinical evidence.
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Collagen Peptides: A Physician's Guide to Types, Benefits, and Evidence
Dr. Douwes reviews the clinical evidence on collagen peptides—types I, II, and III, joint cartilage data, gut healing, skin aging, and how to dose effectively.
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Hashimoto's Thyroiditis: A Functional Medicine Approach to Root-Cause Treatment
Discover how functional medicine addresses Hashimoto's thyroiditis beyond TSH levels—root causes, advanced testing, and evidence-based protocols to reduce antibodies and symptoms.
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Butyrate Supplement Guide: Gut Permeability, Immunity, and SCFA Therapy
A physician's clinical guide to butyrate supplements: mechanisms, evidence for gut permeability and immunity, dosage protocols, and which patients benefit most.
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L-Glutamine for Gut Health: Leaky Gut, Mucosal Repair, and Clinical Dosing
L-glutamine is the intestinal lining's primary fuel source. Explore the clinical evidence for leaky gut, Lyme dysbiosis, post-COVID recovery, and optimal dosing protocols.
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Bovine Colostrum: Clinical Evidence for Immune Modulation and Gut Healing
A physician's review of bovine colostrum supplements — immune IgA, growth factors, leaky gut, and how to use it clinically. Evidence-graded and protocol-ready.
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Akkermansia muciniphila: The Gut Barrier Strain Your Longevity Protocol Is Missing
Akkermansia muciniphila strengthens gut barrier integrity, improves metabolic markers, and predicts immunotherapy response. A clinical review of supplementation evidence.
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SIBO Treatment Protocol: A Functional Medicine Approach to Small Intestinal Bacterial Overgrowth
Clinical guide to diagnosing and treating SIBO with functional medicine — breath testing, rifaximin vs herbal antimicrobials, diet, and relapse prevention.
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BPC-157 Oral vs Injection: Which Route Delivers Better Results?
Physician comparison of BPC-157 oral capsules versus subcutaneous injection — covering bioavailability, onset, dosing, and clinical use cases for each route.
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Best Probiotic Strains by Condition: IBS, Bloating, Immunity, and Mood
Physician guide to evidence-based probiotic strain selection. Which specific strains work for IBS, bloating, immunity, mood, and vaginal health, with dosing and evidence grades.
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How to Choose a Probiotic: CFU Count, Strains, and What Actually Matters
Physician guide to choosing a probiotic supplement. CFU count myths, strain identification, delivery mechanisms, third-party testing, and what the label should tell you.
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KPV for Gut Inflammation: IBD, Colitis, and Clinical Evidence
How the KPV tripeptide reduces gut inflammation. NF-kB inhibition, PepT1 uptake, IBD and colitis evidence, oral dosing, and clinical observations.
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Probiotics vs. Prebiotics vs. Postbiotics: What the Difference Means for Your Gut
Physician guide to probiotics, prebiotics, postbiotics, and synbiotics. Definitions, mechanisms, when to use each, and how they work together for gut health.
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GI-MAP vs Standard Stool Culture: Which Test to Choose
Comparing GI-MAP qPCR stool testing with standard stool culture. Detection rates, pathogen coverage, clinical utility, and when each test is the right choice.
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Lyme Disease, Gut Dysbiosis, and Leaky Gut
How Lyme disease disrupts the gut microbiome. Antibiotic-driven dysbiosis, Borrelia's effect on intestinal permeability, the Hopkins microbiome findings, and recovery strategies.
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How to Read Your Microbiome Test Results
Practical guide to interpreting gut microbiome test results. Dysbiosis markers, keystone species, diversity metrics, and what your results actually mean for treatment.
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Microbiome and Immunity: A Clinical Guide
How gut microbial diversity shapes immune function, and what testing and restoration strategies the evidence supports. By Dr. Julian Douwes.
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Histamine Intolerance: Beyond Allergies
Why histamine intolerance is a systemic condition, not just allergies. Mechanisms, diagnostic pitfalls, gut-immune connections, and treatment strategies from clinical experience.
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Microbiome Testing: Stool Analysis Interpreted
What microbiome stool tests measure, how to interpret results, and which tests provide actionable clinical information. By Dr. Julian Douwes.
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The Gut-Immune Axis: Where Immunity Begins
Why 70% of your immune tissue lives in the gut, and what this means for health, autoimmunity, and treatment. By Dr. Julian Douwes.
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Probiotics: Matching the Right Strain to the Right Condition
Evidence-based guide to probiotic strain selection. Which strains work for which conditions, when to avoid probiotics, CFU counts, spore-based vs traditional, and what I use in clinical practice.
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30-Day Gut Reset Protocol
A structured four-phase protocol for gut restoration -- remove, repair, reinoculate, maintain. Evidence-based by Dr. Julian Douwes.
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Peptide Therapy for Gut Healing
How BPC-157, KPV, and LL-37 support gastrointestinal repair. Dr. Julian Douwes explains peptide protocols for IBD, leaky gut, and gut barrier dysfunction.
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Gut-Brain Axis: How Healing Your Gut Can Transform Brain and Mood Health
The bidirectional gut-brain axis governs mood, cognition, and immune balance. Dr. Julian Douwes explains the science and integrative protocols for restoring this critical communication pathway.
