LDN Titration Schedule: How to Start, Dose, and Optimise Low-Dose Naltrexone
Step-by-step LDN titration guide covering starting dose, weekly escalation, timing, common side effects during ramp-up, and when to pause or plateau.
Clinical Immunology
Moderate EvidenceAutoimmunity
Molecular mimicry, tolerance breakdown, and integrative approaches to autoimmune conditions.
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Ozone Therapy for Autoimmune Disease: Evidence, Patient Selection, and Integration
How medical ozone modulates immune dysregulation in rheumatoid arthritis, lupus, multiple sclerosis, and Hashimoto's — with protocols, contraindications, and outcome data.
03
Black Seed Oil (Nigella Sativa): Thymoquinone's Role in Immune Balance and Inflammation
A physician's evidence-based guide to black seed oil and thymoquinone—dosing, mechanisms, clinical uses in MCAS, autoimmunity, and metabolic health, plus who should avoid it.
04
Low-Dose Naltrexone for Lupus (SLE): Evidence, Dosing, and Clinical Considerations
LDN modulates TLR4 signaling and reduces type-I interferon activity in SLE. Review the clinical evidence, dosing titration, flare monitoring, and drug interactions.
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Low Dose Naltrexone for Psoriatic Arthritis: Evidence, Protocols, and Clinical Insights
How LDN modulates opioid growth factor receptors and neuroinflammation to reduce psoriatic arthritis joint pain and skin flares — dosing, evidence, and who benefits most.
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Who Should NOT Take Ashwagandha: Contraindications, Drug Interactions & Safety Guide
Ashwagandha is generally well-tolerated, but specific groups face real risks. A physician reviews thyroid effects, autoimmune concerns, drug interactions, and who to avoid it.
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Psoriasis: An Integrative Medicine Protocol
A functional medicine approach to psoriasis addressing gut-skin axis, immune modulation, LDN, photobiomodulation, and dietary strategies—backed by clinical evidence.
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Low Dose Naltrexone for Hashimoto's Thyroiditis: Clinical Evidence and Protocol
How LDN modulates thyroid autoimmunity, reduces TPO antibodies, and improves symptoms in Hashimoto's. Dosing protocols, mechanisms, and patient selection criteria.
09
Therapeutic Apheresis: New Indications and Emerging Evidence in 2026
A clinical review of therapeutic apheresis beyond established autoimmune uses—covering neurological, metabolic, and post-infectious indications supported by 2025-2026 evidence.
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Vagus Nerve Stimulation for Rheumatoid Arthritis: Clinical Evidence and Patient Selection
VNS in rheumatoid arthritis — RESET-RA trial results, patient selection criteria, integration with DMARDs, and how bioelectronic medicine is reshaping RA treatment.
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Hashimoto's Thyroiditis: A Functional Medicine Approach to Root-Cause Treatment
Discover how functional medicine addresses Hashimoto's thyroiditis beyond TSH levels—root causes, advanced testing, and evidence-based protocols to reduce antibodies and symptoms.
12
Peptides for Autoimmune Disease: A Physician's Evidence-Based Guide
Discover how immunomodulatory peptides like Thymosin Alpha-1, BPC-157, and LL-37 can help regulate immune dysfunction in autoimmune conditions. Clinical protocols and evidence.
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Low-Dose Naltrexone (LDN): Clinical Evidence for Chronic Illness and Autoimmunity
Low-dose naltrexone modulates immune function and reduces neuroinflammation. Evidence-based overview of LDN dosing, mechanisms, and clinical applications.
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Apheresis for Autoimmune Disease: A Physician's Clinical Guide to Blood Purification Therapy
How extracorporeal apheresis reduces autoantibody burden, inflammatory cytokines, and immune complex load in treatment-resistant autoimmune conditions.
15
Autoimmune Disease: Mechanisms and Treatment
Why the immune system attacks itself, what triggers autoimmunity, and how integrative medicine approaches treatment. By Dr. Julian Douwes.
