Clinical Protocols

Emerging Evidence

Detoxification Protocol

Evidence-based detoxification support — not pseudoscience cleanses.

13 articles · 109 min total
01

Chelation Therapy Safety: Risks, Contraindications, and What to Monitor

A physician's guide to chelation therapy safety — covering EDTA, DMPS, and DMSA risks, contraindications, mineral depletion, and clinical monitoring protocols.

Chelation Therapy Safety: Risks, Contraindications, and What to Monitor
02

Selenium: Thyroid Protection, Antioxidant Defense & Heavy Metal Detox

A physician's guide to selenium dosing, forms, and clinical uses for thyroid health, glutathione recycling, mercury detox, and immune support.

Selenium: Thyroid Protection, Antioxidant Defense & Heavy Metal Detox
03

Phosphatidylcholine: The Essential Phospholipid for Liver, Brain, and Cellular Health

Dr. Douwes explains how phosphatidylcholine supports liver detoxification, cognitive function, and cellular membrane integrity — and who needs it most.

Phosphatidylcholine: The Essential Phospholipid for Liver, Brain, and Cellular Health
04

MTHFR Gene Mutation: Symptoms, Testing, and a Physician's Methylation Protocol

Dr. Douwes explains MTHFR gene variants, how they disrupt methylation and detox, which labs to run, and the evidence-based supplement protocol he uses clinically.

MTHFR Gene Mutation: Symptoms, Testing, and a Physician's Methylation Protocol
05

The Glymphatic System: How Sleep Cleans Your Brain — And What Happens When It Doesn't

The brain's waste-clearance network runs almost exclusively during deep sleep. Learn what the glymphatic system is, how it removes toxic proteins, and how to optimise it clinically.

The Glymphatic System: How Sleep Cleans Your Brain — And What Happens When It Doesn't
06

Sulforaphane and NRF2: The Clinical Case for Broccoli's Most Powerful Compound

Sulforaphane activates the NRF2 pathway to upregulate cellular defenses. A physician's review of clinical evidence, bioavailability, and dosing strategies.

Sulforaphane and NRF2: The Clinical Case for Broccoli's Most Powerful Compound
07

IV Glutathione Therapy: Clinical Uses, Dosing Protocols, and What to Expect

A physician's guide to IV glutathione therapy — indications, dosing protocols, clinical evidence, and how it compares to oral and liposomal forms.

IV Glutathione Therapy: Clinical Uses, Dosing Protocols, and What to Expect
08

Alpha-Lipoic Acid: Neuropathy, Heavy Metal Detox, and Mitochondrial Repair

Dr. Douwes reviews alpha-lipoic acid dosing, R-ALA vs racemic forms, clinical uses for neuropathy, heavy metal chelation support, and mitochondrial longevity.

Alpha-Lipoic Acid: Neuropathy, Heavy Metal Detox, and Mitochondrial Repair
09

Heavy Metal Chelation Therapy: A Physician's Clinical Protocol

Dr. Julian Douwes explains heavy metal chelation therapy — which agents to use, when to use them, how to prepare, and how to monitor safely in clinical practice.

Heavy Metal Chelation Therapy: A Physician's Clinical Protocol
10

What to Expect at Your First Apheresis Session: A Patient's Guide

Step-by-step guide to your first apheresis session. Preparation, procedure, duration, aftercare, and what patients commonly feel — from a physician who performs apheresis daily.

What to Expect at Your First Apheresis Session: A Patient's Guide
11

NAC vs. Glutathione: Which Antioxidant Should You Take?

Physician comparison of NAC vs glutathione supplements. Oral bioavailability, mechanisms, when to use each, liposomal glutathione, and evidence-based recommendations.

NAC vs. Glutathione: Which Antioxidant Should You Take?
12

Managing Herxheimer Reactions at Home

Evidence-based strategies for managing Jarisch-Herxheimer reactions during Lyme treatment — hydration, detox support, dose pacing, and when to call your doctor.

Managing Herxheimer Reactions at Home
13

Gentle Detoxification Protocol

A physician's approach to supporting liver, lymph, and toxin elimination through diet, supplements, and lifestyle. By Dr. Julian Douwes.

Gentle Detoxification Protocol
← Back to Clinical Protocols