Adamax: The Semax Analog With No Published Studies
Adamax is a designer Semax analog with an adamantane cap borrowed from P021. No study has tested it; what is known, what users report, and the dosing in circulation.
Peptide Therapy
Cognitive Peptides
9 articles on Cognitive Peptides by Dr. med. univ. Julian Douwes: Adamax: The Semax Analog With No Published Studies; and more.
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Cerebrolysin: What the Stroke and Dementia Trials Actually Show
Cerebrolysin is a pig-brain peptide drug licensed in Austria and other countries. Cochrane reviews, the CASTA and CARS trials, label doses and community use.
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Cortagen (AEDP): Brain Bioregulator and Nerve-Repair Data
Cortagen (Ala-Glu-Asp-Pro) is a Khavinson brain-cortex tetrapeptide. Rat nerve-regeneration and ischaemia data exist; human evidence is an unpublished claim.
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Intranasal Oxytocin: A Famous Effect That Keeps Failing Replication
Intranasal oxytocin has hundreds of trials and a replication problem. What the large RCTs and registered replications show, how it is dosed, and what users report.
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P021 (P21): The CNTF-Derived Peptide With Only Mouse Data
P021 is a CNTF-derived peptide that boosted neurogenesis and memory in mice and rats. No human study exists. Mechanism, evidence, community dosing and risks.
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PE-22-28 (Mini-Spadin): A TREK-1 Peptide Tested Only in Mice
PE-22-28 is a 7-amino-acid spadin analog that blocks the TREK-1 channel and acted as a fast antidepressant in mice. No human has received it in a study.
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Pinealon (EDR): Brain Bioregulator, Evidence and Dosing
Pinealon (Glu-Asp-Arg) is a Khavinson tripeptide sold for the brain. Cell and mouse data plus one small uncontrolled human study. Evidence, dosing and reports.
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Vesugen (KED): Vascular Bioregulator, Evidence and Dosing
Vesugen (Lys-Glu-Asp) is a Khavinson Cytogen sold for blood vessels. Endothelial cell data, Alzheimer mouse work and one small human study. What it shows.
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Tesamorelin and the Aging Brain: One Trial, Many Questions
A 2012 RCT linked the GHRH analogue tesamorelin to better executive function in older adults. Why one trial is not enough, plus safety and legal status.
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Semax Dosage and Nasal Protocol: A Clinical Guide for Standard, NA-Semax, and the Amidate Form
Precise Semax dosing by variant — 0.1% standard, NA-Semax, NA-Semax Amidate — with cycling schedules, titration steps, and nasal administration technique.
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Nootropic Peptides: A Physician's Guide to Cognitive Enhancement
Compare the top nootropic peptides—Semax, Selank, Dihexa, Humanin, and DSIP—with clinical evidence, dosing protocols, and candidacy criteria from an integrative physician.
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Semax: The Nootropic Peptide That Amplifies BDNF and Protects the Brain
Semax is a synthetic ACTH-derived peptide that upregulates BDNF, enhances focus and memory, and offers neuroprotection — used clinically in Russia for decades.
