Neuromodulation

Cognitive Enhancement

Methylene Blue as a Nootropic: Mitochondrial Mechanisms, Dosing Protocol, and Safety. Part of the Neuromodulation library by Julian Douwes, M.D.

7 articles · 64 min total
01

Lion's Mane Dosage: Physician Protocol for Cognitive and Nerve Benefits

Evidence-based lion's mane dosage guide covering optimal doses for cognition, neuropathy, and gut health—plus timing, cycling, forms, and who should avoid it.

Lion's Mane Dosage: Physician Protocol for Cognitive and Nerve Benefits
02

Methylene Blue as a Nootropic: Mitochondrial Mechanisms, Dosing Protocol, and Safety

Methylene blue enhances mitochondrial electron transport, improves memory, and reduces brain fog. Learn dosing protocols, evidence, and key safety limits.

Methylene Blue as a Nootropic: Mitochondrial Mechanisms, Dosing Protocol, and Safety
03

Bacopa Monnieri: A Physician's Evidence-Based Guide to Cognitive Enhancement and Stress Resilience

Bacopa monnieri improves memory, reduces anxiety, and protects neurons. Discover the clinical evidence, optimal dosing, forms, and who benefits most from this Ayurvedic nootropic.

Bacopa Monnieri: A Physician's Evidence-Based Guide to Cognitive Enhancement and Stress Resilience
04

Semax Dosage and Nasal Protocol: A Clinical Guide for Standard, NA-Semax, and the Amidate Form

Precise Semax dosing by variant — 0.1% standard, NA-Semax, NA-Semax Amidate — with cycling schedules, titration steps, and nasal administration technique.

Semax Dosage and Nasal Protocol: A Clinical Guide for Standard, NA-Semax, and the Amidate Form
05

Methylene Blue Dosage Guide: Clinical Protocols, Forms, and Safety

Evidence-based methylene blue dosage guide covering cognitive, mitochondrial, and antimicrobial applications with safety protocols and contraindications.

Methylene Blue Dosage Guide: Clinical Protocols, Forms, and Safety
06

Nootropic Peptides: A Physician's Guide to Cognitive Enhancement

Compare the top nootropic peptides—Semax, Selank, Dihexa, Humanin, and DSIP—with clinical evidence, dosing protocols, and candidacy criteria from an integrative physician.

Nootropic Peptides: A Physician's Guide to Cognitive Enhancement
07

Semax: The Nootropic Peptide That Amplifies BDNF and Protects the Brain

Semax is a synthetic ACTH-derived peptide that upregulates BDNF, enhances focus and memory, and offers neuroprotection — used clinically in Russia for decades.

Semax: The Nootropic Peptide That Amplifies BDNF and Protects the Brain
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