Longevity Medicine
Emerging EvidenceSelective elimination of senescent cells to reduce chronic inflammation and aging.
A physician's guide to the D+Q senolytic combination — clinical evidence, dosing schedule, cycling intervals, patient selection, and lab monitoring for longevity practice.
Pterostilbene offers 4× greater bioavailability than resveratrol with longer half-life. Compare clinical evidence, dosing, and Dr. Douwes's protocol for stilbene supplementation.
Inflammaging drives biological aging, cardiovascular disease, and neurodegeneration. Learn the science, key biomarkers, and evidence-based interventions from an integrative physician.
How mTOR drives cellular aging, which compounds inhibit it, and why targeting this pathway is central to modern longevity medicine. Clinical overview by Dr. Julian Douwes.
A physician's evidence-based guide to rapamycin dosing for longevity: weekly intermittent protocols, dose ranges, lab monitoring, and who should avoid it.
Apigenin inhibits CD38 to raise NAD+ levels, clears senescent cells, and deepens sleep. A physician's evidence-based guide to dosing, stacking, and safety.
A physician's comparison of fisetin and quercetin as senolytic agents — mechanisms, evidence, dosing protocols, and which patients benefit from each flavonoid.
Physician guide to quercetin senolytic protocols. Quercetin + dasatinib evidence, quercetin + fisetin alternatives, dosing schedules, and the science of clearing senescent cells.
How senolytic therapies target zombie cells that drive aging. Dasatinib, quercetin, fisetin -- evidence, protocols, and honest limitations.
How to activate autophagy through fasting, exercise, and targeted interventions. The science of cellular self-cleaning, its role in aging, and what actually works.
Fisetin senolytic dosing, Mayo Clinic research, mechanism of action, combination with quercetin, and honest evidence grading from a physician who uses senolytics in clinical practice.
