Trimethylglycine (TMG/Betaine): Methylation Support, Homocysteine, and Longevity
TMG donates methyl groups to lower homocysteine, support liver function, and enhance athletic performance. Clinical dosing, evidence, and who benefits most.
Longevity Medicine
Methylation
Homocysteine: What Your Levels Mean and How to Lower Them. Part of the Longevity Medicine library by Dr. med. univ. Julian Douwes
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Epigenetic Clock Tests Compared: TruAge, GlycanAge, and OMICmAge
Head-to-head comparison of the top commercial biological age tests — TruAge, GlycanAge, and OMICmAge — to help you choose the right panel for your longevity goals.
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Homocysteine: What Your Levels Mean and How to Lower Them
High homocysteine quietly damages blood vessels and the brain. A physician explains optimal ranges, root causes like MTHFR, and evidence-based ways to lower it.
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Methylcobalamin vs. Cyanocobalamin: A Physician's Guide to B12 Supplementation
Dr. Douwes breaks down every B12 form — methylcobalamin, adenosylcobalamin, hydroxocobalamin — covering dosing, testing, and who truly benefits from active B12.
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Glycine: The Amino Acid Behind Better Sleep, Collagen, and Longevity
Glycine at 3 g before bed improves sleep quality in RCTs. As a longevity molecule it drives collagen synthesis, glutathione via GlyNAC, and mTOR modulation.
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MTHFR Gene Mutation: Symptoms, Testing, and a Physician's Methylation Protocol
Dr. Douwes explains MTHFR gene variants, how they disrupt methylation and detox, which labs to run, and the evidence-based supplement protocol he uses clinically.
