Infectiology

Emerging Evidence

Biofilms

How bacterial biofilms protect persistent infections and strategies to disrupt them.

11 articles · 84 min total
01

Dapsone, Disulfiram, and Azlocillin in Lyme Disease: Combination Protocols for Persister Cells

An evidence-based review of emerging repurposed-drug protocols—dapsone, disulfiram, and azlocillin—targeting Borrelia persister cells in chronic Lyme disease.

Dapsone, Disulfiram, and Azlocillin in Lyme Disease: Combination Protocols for Persister Cells
02

Lumbrokinase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?

Comparing lumbrokinase and nattokinase for fibrin clearance, biofilm disruption, post-COVID microclots, and cardiovascular health — with clinical dosing guidance.

Lumbrokinase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?
03

Serrapeptase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?

A physician-led comparison of serrapeptase and nattokinase: mechanisms, clinical evidence, dosing, and which fibrinolytic enzyme fits your health goals.

Serrapeptase vs Nattokinase: Which Fibrinolytic Enzyme Is Right for You?
04

Serrapeptase Anti-Inflammatory Enzyme: Clinical Evidence and Dosing Guide

A physician's guide to serrapeptase: how this proteolytic enzyme reduces inflammation, breaks down biofilm, and compares to NSAIDs — with evidence-based dosing.

Serrapeptase Anti-Inflammatory Enzyme: Clinical Evidence and Dosing Guide
05

Lumbrokinase: The Fibrinolytic Enzyme Your Doctor Probably Hasn't Mentioned

Lumbrokinase is a potent fibrinolytic enzyme with emerging evidence for post-COVID microclots, Lyme biofilms, and chronic inflammation. A physician's clinical overview.

Lumbrokinase: The Fibrinolytic Enzyme Your Doctor Probably Hasn't Mentioned
06

Ozone Therapy for Lyme Disease: Clinical Evidence, Protocols & What to Expect

How ozone therapy works against Borrelia and co-infections, which protocols are used clinically, and what published evidence says about its role in Lyme care.

Ozone Therapy for Lyme Disease: Clinical Evidence, Protocols & What to Expect
07

Why Antibiotics Alone Fail Against Biofilms

How bacterial biofilms reduce antibiotic efficacy by 100-1,000x, why standard treatment courses miss persistent infections, and what integrative approaches add.

Why Antibiotics Alone Fail Against Biofilms
08

Nattokinase and Serrapeptase for Biofilm Disruption

How proteolytic enzymes nattokinase and serrapeptase degrade biofilm matrix components — mechanism, dosing, evidence, and clinical considerations.

Nattokinase and Serrapeptase for Biofilm Disruption
09

Biofilm Disruption Protocols for Chronic Infections

A clinical overview of biofilm disruption strategies for persistent Lyme disease — the three-phase approach of disrupt, kill, and clear.

Biofilm Disruption Protocols for Chronic Infections
10

LL-37 for Biofilm Disruption in Chronic Lyme

How LL-37 disrupts Borrelia biofilms in chronic Lyme disease. Mechanism, preclinical evidence, protocol context, and clinical observations.

LL-37 for Biofilm Disruption in Chronic Lyme
11

Biofilms: Why Infections Persist

How biofilms protect chronic infections from antibiotics and the immune system. Disruption strategies and clinical implications.

Biofilms: Why Infections Persist
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