Senolytics: Who Should NOT Take Them — A Physician's Safety Guide
A clinical guide to senolytics contraindications: active cancer, cardiac risk, drug interactions, active infection, and the 2026 demyelination finding from PNAS.
Supplements
Emerging EvidenceQuercetin
Senolytic, antihistamine, and zinc ionophore properties — what the evidence shows.
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Senolytics for Osteoporosis: How Clearing Senescent Cells Can Restore Bone Density
The case for senolytic therapy in osteoporosis: how zombie cells disrupt bone remodeling, what the 2024 Phase 2 trial showed, and which patients benefit most.
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Dasatinib + Quercetin Senolytic Protocol: Dosing, Cycling, and Clinical Evidence
A physician's guide to the D+Q senolytic combination — clinical evidence, dosing schedule, cycling intervals, patient selection, and lab monitoring for longevity practice.
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Fisetin vs Quercetin: Which Senolytic Flavonoid Is Better?
A physician's comparison of fisetin and quercetin as senolytic agents — mechanisms, evidence, dosing protocols, and which patients benefit from each flavonoid.
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Quercetin as a Senolytic: Protocol, Dosage, and What the Research Shows
Physician guide to quercetin senolytic protocols. Quercetin + dasatinib evidence, quercetin + fisetin alternatives, dosing schedules, and the science of clearing senescent cells.
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Nattokinase: The Fibrinolytic Enzyme for Microclots
Evidence-based guide to nattokinase for fibrinolysis and microclots. Mechanism, dosing, post-COVID relevance, combination with serrapeptase, and safety with blood thinners.
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Lion's Mane: Nerve Growth Factor and Cognitive Benefits
Evidence-based guide to lion's mane mushroom for brain health. NGF stimulation, cognitive benefits, dosing, extract types, and what the clinical data supports.
