Low Dose Naltrexone (LDN) as a Cancer Adjunct: Mechanisms, Evidence, and Clinical Protocol
How LDN modulates OGF/OGFr signaling, upregulates NK cell activity, and may reduce tumor growth—with dosing protocols and candidate selection criteria.
Clinical Immunology
Moderate EvidenceNatural killer cell function, testing, and therapeutic enhancement.
How LDN modulates OGF/OGFr signaling, upregulates NK cell activity, and may reduce tumor growth—with dosing protocols and candidate selection criteria.
Trained immunity is epigenetic reprogramming of innate immune cells that boosts long-term pathogen defence without T or B cells. Here is what it means clinically.
The immune suppression cascade: how Lyme disease triggers EBV, HHV-6, and CMV reactivation, and how these viruses further suppress immunity in a vicious cycle.
Understanding low natural killer cell function in chronic illness. What NK cells do, why function drops, how to test, and evidence-based strategies to restore immune surveillance.
What NK cells do, why CD57 matters in Lyme disease, and how to support natural killer cell function. By Dr. Julian Douwes.