ACE-031: The Myostatin Blocker That Was Stopped, and Why
ACE-031 added 3.3% lean mass from one dose, then its Duchenne trial was halted over nosebleeds and telangiectasias. What happened and what it teaches.
Peptide Therapy
6 articles on Growth Hormones by Dr. med. univ. Julian Douwes: ACE-031: The Myostatin Blocker That Was Stopped, and Why; and more.
ACE-031 added 3.3% lean mass from one dose, then its Duchenne trial was halted over nosebleeds and telangiectasias. What happened and what it teaches.
Follistatin blocks myostatin and activin. The human evidence is gene therapy in muscular dystrophy and myositis, not injected protein. Protocols and law.
IGF-1 LR3 is an engineered IGF-1 analogue that evades binding proteins. What the animal and native-IGF-1 data show, the protocols used, and the real risks.
MGF is the IGF-1Ec splice variant switched on by mechanical loading. What the muscle biology shows, why two pharma labs could not reproduce the peptide effect.
PEG-MGF is PEGylated mechano growth factor, built to fix MGF's short half-life. FDA found no human exposure data. What the evidence, protocols and law say.
Evidence-based review of peptides for muscle growth. GH secretagogues, BPC-157 for recovery, safety risks, and where the human evidence stops.