Clinical Immunology

Moderate Evidence

Gut-Immune Axis

The microbiome-immune connection and mucosal immunity.

14 articles · 101 min total
01

How to Read Your Microbiome Test Results

Practical guide to interpreting gut microbiome test results. Dysbiosis markers, keystone species, diversity metrics, and what your results actually mean for treatment.

How to Read Your Microbiome Test Results
02

GI-MAP vs Standard Stool Culture: Which Test to Choose

Comparing GI-MAP qPCR stool testing with standard stool culture. Detection rates, pathogen coverage, clinical utility, and when each test is the right choice.

GI-MAP vs Standard Stool Culture: Which Test to Choose
03

Lyme Disease, Gut Dysbiosis, and Leaky Gut

How Lyme disease disrupts the gut microbiome. Antibiotic-driven dysbiosis, Borrelia's effect on intestinal permeability, the Hopkins microbiome findings, and recovery strategies.

Lyme Disease, Gut Dysbiosis, and Leaky Gut
04

Histamine Intolerance: Beyond Allergies

Why histamine intolerance is a systemic condition, not just allergies. Mechanisms, diagnostic pitfalls, gut-immune connections, and treatment strategies from clinical experience.

Histamine Intolerance: Beyond Allergies
05

KPV for Gut Inflammation: IBD, Colitis, and Clinical Evidence

How the KPV tripeptide reduces gut inflammation. NF-kB inhibition, PepT1 uptake, IBD and colitis evidence, oral dosing, and clinical observations.

KPV for Gut Inflammation: IBD, Colitis, and Clinical Evidence
06

Probiotics: Matching the Right Strain to the Right Condition

Evidence-based guide to probiotic strain selection. Which strains work for which conditions, when to avoid probiotics, CFU counts, spore-based vs traditional, and what I use in clinical practice.

Probiotics: Matching the Right Strain to the Right Condition
07

Best Probiotic Strains by Condition: IBS, Bloating, Immunity, and Mood

Physician guide to evidence-based probiotic strain selection. Which specific strains work for IBS, bloating, immunity, mood, and vaginal health, with dosing and evidence grades.

Best Probiotic Strains by Condition: IBS, Bloating, Immunity, and Mood
08

How to Choose a Probiotic: CFU Count, Strains, and What Actually Matters

Physician guide to choosing a probiotic supplement. CFU count myths, strain identification, delivery mechanisms, third-party testing, and what the label should tell you.

How to Choose a Probiotic: CFU Count, Strains, and What Actually Matters
09

Probiotics vs. Prebiotics vs. Postbiotics: What the Difference Means for Your Gut

Physician guide to probiotics, prebiotics, postbiotics, and synbiotics. Definitions, mechanisms, when to use each, and how they work together for gut health.

Probiotics vs. Prebiotics vs. Postbiotics: What the Difference Means for Your Gut
10

Microbiome Testing: Stool Analysis Interpreted

What microbiome stool tests measure, how to interpret results, and which tests provide actionable clinical information. By Dr. Julian Douwes.

Microbiome Testing: Stool Analysis Interpreted
11

The Gut-Immune Axis: Where Immunity Begins

Why 70% of your immune tissue lives in the gut, and what this means for health, autoimmunity, and treatment. By Dr. Julian Douwes.

The Gut-Immune Axis: Where Immunity Begins
12

Microbiome and Immunity: A Clinical Guide

How gut microbial diversity shapes immune function, and what testing and restoration strategies the evidence supports. By Dr. Julian Douwes.

Microbiome and Immunity: A Clinical Guide
13

Peptide Therapy for Gut Healing

How BPC-157, KPV, and LL-37 support gastrointestinal repair. Dr. Julian Douwes explains peptide protocols for IBD, leaky gut, and gut barrier dysfunction.

Peptide Therapy for Gut Healing
14

30-Day Gut Reset Protocol

A structured four-phase protocol for gut restoration -- remove, repair, reinoculate, maintain. Evidence-based by Dr. Julian Douwes.

30-Day Gut Reset Protocol
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