Longevity Medicine

Moderate Evidence

Rapamycin

mTOR inhibition for lifespan extension — the most replicated result in aging research.

2 articles · 16 min total
01

Rapamycin vs Metformin for Longevity: A Head-to-Head Comparison

A physician's honest comparison of rapamycin and metformin for longevity. mTOR inhibition vs AMPK activation, evidence quality, dosing, and who should use which.

Apr 1, 2026 · 11 min read
Rapamycin vs Metformin for Longevity: A Head-to-Head Comparison
02

Rapamycin and mTOR: Longevity's Most Debated Drug

How rapamycin inhibits mTOR to potentially slow aging. Evidence from animal studies, emerging human data, risks, and honest assessment.

Mar 28, 2026 · 5 min read
Rapamycin and mTOR: Longevity's Most Debated Drug
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